SVR-LSMgui (v0.15) Output Overview


Analysis summary

This analysis named 'Mless_DTLVC' tested the hypothesis (high scores are good) that there is a relationship between lesion status and the behavior score 'x_AVG'. 73 subjects were listed for inclusion, and 0 were excluded due to missing behavioral data, lesion data, or for having no voxels inside the minimum lesion cutoff mask (). Each lesion volume was binarized prior to the analysis. Data was corrected for lesion volume via DTLVC. No other covariates were specified. The resulting SVR-β values were thresholded at p < .05 and corrected for cluster size at p < .05, both based on 10000 permutations. The analysis was restricted to voxels with at least 7 overlapping lesions. The analysis was run on 25-Sep-2019 using MATLAB's SVR procedures (parallelized, not run from the GUI), with parameters gamma = 5 and cost = 30. SVR-β maps were generated using 5-fold cross-validation.Hyperparameter optimization was not utilized. The analysis completed in 29 hours and 16 minutes.


Lesion overlaps

Overlap of lesions in the patient sample (N = 73), a green outline indicates regions meeting the minimum lesion overlap criterion for the analysis (N = 7) totaling 300515 or approximately 44% of the 676627 voxels with any lesions present.

Overlap of lesions in the patient sample (N = 73), a green outline indicates regions meeting the minimum lesion overlap criterion for the analysis (N = 7) totaling 300515 or approximately 44% of the 676627 voxels with any lesions present.<br>


Unthresholded SVR-β map

Unthresholded SVR-β map


Voxelwise thresholded Z(P) Values

Voxelwise thresholded Z(P) values, p < 0.05 based on 10000 permutations.
Voxelwise thresholded Z(P) values, p < 0.05 based on 10000 permutations.

Clusterwise thresholded P-map

1 cluster was significant at p < .05 based on 10000 permutations.

Labeled significant clusters, p < 0.05 based on 10000 permutations.
Labeled significant clusters, p < 0.05 based on 10000 permutations.


Behavioral nuisance model diagnostics

No behavioral nuisance model was included, so no diagnostics to display.


Cluster correction threshold stability

Cluster size stability over 10000 permutations, assessed every 100 permutations. Also plotted are up to 5 clusters regardless of significance for comparison to critical threshold.
Cluster size stability over 10000 permutations, assessed every 100 permutations. Also plotted are up to 5 clusters regardless of significance for comparison to critical threshold.


Hyperparameter Quality Report

The final SVR model did converge. The model had parameters Cost/BoxConstraint = 30.00, Sigma/KernelScale = 0.45, Epsilon = 0.10, and Standardize = true. The final model utilized data points from 73 of the 73 observations (individual subjects) as support vectors. The final model had a bias of 68.22. Average prediction accuracy is -0.22 (SD = 0.09) and average reproducibility index is r = 0.80 (SD = 0.07). Average mean absolute difference between real and predicted behaviors is 12.73 (SD = 0.11).

Parameter quality plots